Article

The Immune System – Friend or Foe for Adenovirus Based Therapies?

2024-05-27

Abstract excerpt

Pathogenic adenovirus (Ad) infections are widespread but typically mild and transient, except in the immunocompromised. As vectors for gene therapy, vaccine and oncology applications, Ad based platforms offer advantages including ease of genetic manipulation, scale of production and well established safety profiles, making them attractive tools for therapeutic development. However, the immune system often poses a...

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Literature Corpus work: f07e3c9d-cfda-530b-9dc3-d88706a39d80
DOI: 10.20944/preprints202405.1698.v1

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