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Adenoviruses as gene/vaccine delivery vectors: promises and pitfalls

22 Dec 2014

Abstract excerpt

INTRODUCTION: Adenoviruses (Ads) have attracted researchers from across the disciplines for several reasons. Their ability to recombine with and express the heterologous genes encouraged their development as gene/vaccine delivery vectors. Preclinical and clinical trials using these vectors have shown significant promise for their future development while highlighting certain limitations. AREAS COVERED: Ad vector...

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PMID: 25529044
DOI: 10.1517/14712598.2015.993374

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