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Article

The Innate Immune Response to Adenovirus Vectors

1 Dec 2004

Abstract excerpt

Gene therapy is a clinical strategy that may potentially treat an array of genetic and nongenetic diseases, as well as a novel method for drug delivery and vaccination. To these ends, adenovirus vectors are a promising means to deliver specific genes of interest into the patient. A major limitation of the use of adenovirus vectors is the host immune response. Adenovirus vectors induce the innate arm of the immune...

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Identifiers

PMID: 15684693
DOI: 10.1089/hum.2004.15.1157

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