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Article

Immune Recognition of Gene Transfer Vectors: Focus on Adenovirus as a Paradigm

1 Jan 2011

Abstract excerpt

Recombinant Adenovirus (Ad) based vectors have been utilized extensively as a gene transfer platform in multiple pre-clinical and clinical applications. These applications are numerous, and inclusive of both gene therapy and vaccine based approaches to human or animal diseases. The widespread utilization of these vectors in both animal models, as well as numerous human clinical trials (Ad-based vectors surpass...

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Share to RNA Interference and Gene Delivery
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PMID: 22566830
DOI: 10.3389/fimmu.2011.00040

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