Article

BCL2L13 attenuation links impaired mitophagy to epithelial plasticity and anoikis tolerance in lung adenocarcinoma

2026-08-31

Abstract excerpt

BCL2L13 is a mitochondrial BCL2 family protein linked to mitophagy and ceramide metabolism, but its role in NSCLC metastatic plasticity remains unclear. Human lung cancer Tissue Microarray and matched patient specimens showed subtype and site dependent BCL2L13 expression, with higher cytoplasmic granular staining in primary NSCLC and reduced, heterogeneous staining in lymph node metastases, most evident in adenoca...

Identifiers and source

Literature Corpus work: f07b2917-4849-5a74-8ad4-4597fd87b003
DOI: 10.64898/2026.08.28.747809

Open publication

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