Article

Longitudinal multi-omic signatures of ARDS and sepsis inflammatory phenotypes identify key pathways associated with mortality

2025-05-08

Abstract excerpt

Critically ill patients with acute respiratory distress syndrome (ARDS) and sepsis exhibit distinct inflammatory phenotypes with divergent clinical outcomes and apparent heterogeneity of treatment effects, but the underlying molecular mechanisms remain poorly understood. These phenotypes, derived from clinical data and protein biomarkers, were associated with metabolic differences in a prior pilot study. This stud...

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Literature Corpus work: f067f86a-447a-5964-ba0c-83ca32e7769e
DOI: 10.1101/2025.05.07.25327117

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