Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasma metabolic profiling implicates dysregulated lipid metabolism and glycolytic shift in hyperinflammatory ARDS.

American journal of physiology. Lung cellular and molecular physiology - 1 Mar 2023

Alipanah-Lechner Narges, Neyton Lucile, Mick Eran, Willmore Andrew, Leligdowicz Aleksandra, Contrepois Kévin, Jauregui Alejandra, Zhuo Hanjing, Hendrickson Carolyn, Gomez Antonio, Sinha Pratik, Kangelaris Kirsten N, Liu Kathleen D, Matthay Michael A, Rogers Angela J, Calfee Carolyn S

Abstract excerpt

Using latent class analysis (LCA) of clinical and protein biomarkers, researchers have identified two phenotypes of the acute respiratory distress syndrome (ARDS) with divergent clinical trajectories and treatment responses. We investigated whether plasma metabolites differed among patients with LCA-derived hyperinflammatory and hypoinflammatory ARDS, and we tested the prognostic utility of adding metabolic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Lipid Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Respiratory Distress Syndrome

Source

Open in PubMed Open full text

Identifiers

PMID: 36648136
DOI: 10.1152/ajplung.00278.2022
PMCID: PMC9988532

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasma metabolic profiling implicates dysregulated lipid metabolism and glycolytic shift in hyperinflammatory ARDS.PMID 36648136Read ↗

Longitudinal multi-omic signatures of ARDS and sepsis inflammatory phenotypes identify key pathways associated with mortalitySemantic proximity Read ↗

Longitudinal multiomic signatures of ARDS and sepsis inflammatory phenotypes identify pathways associated with mortality.Semantic proximity Read ↗

Metabolic septic shock sub-phenotypes, stability over time and association with clinical outcome.Semantic proximity Read ↗

Personalized medicine using omics approaches in acute respiratory distress syndrome to identify biological phenotypes.Semantic proximity Read ↗

Applying metabolomics to uncover novel biology in ARDSSemantic proximity Read ↗

Host and Microbe Blood Metagenomics Reveals Key Pathways Characterizing Critical Illness Phenotypes.Semantic proximity Read ↗

Large-scale proteomic profiling identifies distinct inflammatory phenotypes in acute respiratory distress syndrome: a multicentre, prospective cohort study.Semantic proximity Read ↗

Metabolic Biomarkers and Endotypes as Predictors of Sepsis Outcomes: A Prospective Population-Based Cohort Analysis from the UK BiobankSemantic proximity Read ↗

Patient Stratification in Sepsis: Using Metabolomics to Detect Clinical Phenotypes, Sub-Phenotypes and Therapeutic ResponseSemantic proximity Read ↗

Metabolic phenotyping of sepsis in large multicenter cohorts: identification of a reproducible high-risk subgroup.Semantic proximity Read ↗

Elevated serum apolipoprotein B and lipoprotein remodelling distinguish adults with HLH from HLH mimics and controlsSemantic proximity Read ↗

High-throughput mass spectrometry maps the sepsis plasma proteome and differences in patient responseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.