Article

Deciphering sepsis molecular subtypes using large-scale data to identify subtype-specific drug repurposing

2026-03-30

Abstract excerpt

Sepsis is a life-threatening dysregulated response to infection, the heterogeneity of which precludes effective targeted therapies. To address this, we created a transcriptomic atlas of publicly available adult sepsis data, on which we performed molecular subtyping and identified potential subtype-specific drug repurposing opportunities. In total, we harmonized data from 3,713 samples across 28 datasets, of which...

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Literature Corpus work: d2c462ad-1573-5fe4-9792-ce4affca588b
DOI: 10.64898/2026.03.28.714506

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