Article
High-throughput mass spectrometry maps the sepsis plasma proteome and differences in response
2022-08-09
Abstract excerpt
<h4>Summary</h4> Sepsis, the dysregulated host response to infection causing life-threatening organ dysfunction, is an unmet global health challenge. Here we apply high-throughput tandem mass spectrometry to delineate the plasma proteome for sepsis and comparator groups (non-infected critical illness, post-operative inflammation and healthy volunteers) involving 2622 samples and 4553 liquid chromatography-mass spe...
Topics
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- Advanced Proteomics Techniques and Applications
- Bacterial Identification and Susceptibility Testing
- Inflammation biomarkers and pathways
- Metabolomics and Mass Spectrometry Studies
- Neonatal and Maternal Infections
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- S100 Proteins and Annexins
- Sepsis Diagnosis and Treatment
Identifiers and source
- Literature Corpus work
- d6401fba-78dc-5c1a-a86f-1dcb67480ba6
- DOI
- 10.1101/2022.08.07.22278495
