Article
Selection shapes malaria genomes and drives divergence between pathogens infecting hominids versus rodents.
BMC evolutionary biology - 30 Jul 2008
Prugnolle Franck, McGee Kate, Keebler Jon, Awadalla Philip
Abstract excerpt
BACKGROUND: Malaria kills more people worldwide than all inherited human genetic disorders combined. To characterize how the parasites causing this disease adapt to different host environments, we compared the evolutionary genomics of two distinct groups of malaria pathogens in order to identify critical properties associated with infection of different hosts: those parasites infecting hominids (Plasmodium...
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