Article
The role of protozoa-driven selection in shaping human genetic variability.
Trends in genetics : TIG - 1 Mar 2010
Pozzoli Uberto, Fumagalli Matteo, Cagliani Rachele, Comi Giacomo P, Bresolin Nereo, Clerici Mario, Sironi Manuela
Abstract excerpt
Protozoa exert a strong selective pressure in humans. The selection signatures left by these pathogens can be exploited to identify genetic modulators of infection susceptibility. We show that protozoa diversity in different geographic locations is a good measure of protozoa-driven selective pres...
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