Article

Laminin fragments conjugated with perlecan’s growth factor–binding domain differentiate human induced pluripotent stem cells into skin dermal stem cells

2023-01-04

Abstract excerpt

Deriving stem cells to regenerate full-thickness human skin is important for treating skin disorders without invasive surgical procedures. Our previous protocol to differentiate human induced pluripotent stem cells (iPSCs) into skin-derived precursor cells (SKPs) as a source of dermal stem cells employs mouse fibroblasts as feeder cells and is therefore unsuitable for clinical use. Herein, we report a feeder-free...

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Literature Corpus work: f025dea5-2db7-5003-95d4-7e3b542620ba
DOI: 10.21203/rs.3.rs-2366281/v1

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