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A Comparative View on Human Somatic Cell Sources for iPSC Generation

1 Jan 2014

Abstract excerpt

The breakthrough of reprogramming human somatic cells was achieved in 2006 by the work of Yamanaka and Takahashi. From this point, fibroblasts are the most commonly used primary somatic cell type for the generation of induced pluripotent stem cells (iPSCs). Various characteristics of fibroblasts supported their utilization for the groundbreaking experiments of iPSC generation. One major advantage is the high...

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PMID: 25431601
DOI: 10.1155/2014/768391

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