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Generating Skin‐Derived Precursor‐Like Cells From Human‐Induced Pluripotent Stem Cell‐Derived Skin Organoids

1 Nov 2024

Abstract excerpt

Skin-derived precursor (SKPs) cells are multipotent stem cells found in the dermis that contribute to wound healing and induce hair follicle neogenesis when transplanted. The clinical application of adult human SKPs, however, is hindered by their loss of potency after in vitro expansion. To overcome this challenge, we aimed to isolate SKPs from human-induced pluripotent stem cell-derived skin organoids (SKOs), to...

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PMID: 39582396
DOI: 10.1111/exd.70017

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