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Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids

12 May 2022

Abstract excerpt

Human induced pluripotent stem cell (hiPSC)-derived hair-bearing skin organoids offer exciting new possibilities for modeling diseases like epidermolysis bullosa (EB). These inherited diseases affect 1 in 30,000 people worldwide and result from perturbed expression and/or structure of components of the epidermal-dermal junction (EDJ). To establish whether hiPSC-derived skin organoids might be able to capture...

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PMID: 35561682
DOI: 10.1016/j.stemcr.2022.04.008

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