Article

Global landscape of mouse and human cytokine transcriptional regulation

2018-05-09

Abstract excerpt

Cytokines play a central role in immune development, pathogen responses, and diseases. Cytokines are highly regulated at the transcriptional level by combinations of transcription factors (TFs) that recruit cofactors and the transcriptional machinery. Here, we review three decades of studies to generate a comprehensive database reporting 843 and 647 interactions between TFs and cytokines genes, in human and mouse...

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Literature Corpus work: f01dd845-ea76-5222-8b65-d66e5a1a133e
DOI: 10.1101/316612

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