Article

Conservation and divergence in modules of the transcriptional programs of the human and mouse immune systems

2018-03-22

Abstract excerpt

Studies in mouse have shed important light on human hematopoietic differentiation and disease. However, substantial differences between the two species often limit the translation of findings from mouse to human. Here, we compare previously defined modules of co-expressed genes in human and mouse immune cells based on compendia of genome-wide profiles. We show that the overall modular organization of the transcrip...

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Literature Corpus work: 415677e7-266d-541c-a884-1b9fdbca4746
DOI: 10.1101/286211

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