Article
Immunotherapy of Primary Brain Tumors: Facts and Hopes.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2018
Buerki Robin A, Chheda Zinal S, Okada Hideho
Abstract excerpt
The field of cancer immunotherapy has made exciting progress for some cancer types in recent years. However, recent failures of late-phase clinical trials evaluating checkpoint blockade in patients with glioblastoma (GBM) represent continued challenges for brain cancer immunotherapy. This is likely due to multiple factors including but not limited to marked genetic and antigenic heterogeneity, relatively low...
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