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Article

The Role of Macrophages in Atherosclerosis: Pathophysiologic Mechanisms and Treatment Considerations.

International journal of molecular sciences - 31 May 2023

Theofilis Panagiotis, Oikonomou Evangelos, Tsioufis Konstantinos, Tousoulis Dimitris

Abstract excerpt

Atherosclerotic diseases are a leading cause of morbidity and mortality worldwide, despite the recent diagnostic and therapeutic advances. A thorough understanding of the pathophysiologic mechanisms is thus essential to improve the care of affected individuals. Macrophages are crucial mediators of the atherosclerotic cascade, but their role has not been fully elucidated. The two main subtypes, tissue-resident and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37298518
DOI: 10.3390/ijms24119568
PMCID: PMC10253295

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