Article

The retinal RNA editome is concentrated in photoreceptor-specific genes and genetically linked to vision loss

2023-06-24

Abstract excerpt

<h4>ABSTRACT</h4> <h4>BACKGROUND</h4> Conversion of adenosine in RNA to inosine by ADAR enzymes, termed ‘RNA editing’, occurs at thousands of sites across the transcriptome, and is required for healthy development of the central nervous system. RNA editing can modify protein sequences, and dampen the innate immune response. RNA editing is tissue-specific and partly genetically determined. Modifications of RNA ed...

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Literature Corpus work: ef91fe1c-67be-5ab2-bc8b-13465899c5d6
DOI: 10.1101/2023.06.22.543349

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