Article

Epigenomic Profiling and Single-Nucleus-RNA-Seq Reveal <i>Cis</i> -Regulatory Elements in Human Retina, Macula and RPE and Non-Coding Genetic Variation

2018-09-08

Abstract excerpt

<h4>ABSTRACT</h4> Cis -regulatory elements (CREs) orchestrate the dynamic and diverse transcriptional programs that assemble the human central nervous system (CNS) during development and maintain its function throughout life. Genetic variation within CREs plays a central role in phenotypic variation in complex traits including the risk of developing disease. However, the cellular complexity of the human brain has...

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Literature Corpus work: 45815f07-0492-5201-9a05-6c3679321eef
DOI: 10.1101/412361

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