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Article

The herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latency.

Journal of virology - 1 Jul 1997

Thompson R L, Sawtell N M

Abstract excerpt

Herpes simplex virus type 1 establishes latent infections in sensory neurons. During latency only one locus, the latency-associated transcript (LAT), is abundantly transcribed. Several lines of evidence suggest that this locus is required for the efficient reactivation from latency in experimental models. However, it is not yet clear whether this is a direct effect on the reactivation process per se or, as we...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 9188615
DOI: 10.1128/JVI.71.7.5432-5440.1997
PMCID: PMC191783

Genes

LAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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The herpes simplex virus type 1 latency-associated transcript gene regulates the establishment of latency.PMID 9188615Read ↗

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Herpes simplex virus type 1 latency-associated transcription unit promotes anatomical site-dependent establishment and reactivation from latency.Semantic proximity Read ↗

Experimental investigation of herpes simplex virus latencySemantic proximity Read ↗

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The molecular basis of herpes simplex virus latencySemantic proximity Read ↗

A LAT-associated function reduces productive-cycle gene expression during acute infection of murine sensory neurons with herpes simplex virus type 1Semantic proximity Read ↗

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