Article

The E3 ubiquitin ligase MIB-1 is necessary to form the nuclear halo in <i>C. elegans</i> sperm

2018-04-14

Abstract excerpt

Unlike the classical nuclear envelope with two membranes found in other eukaryotic cells, most nematode sperm nuclei are not encapsulated by membranes. Instead, they are surrounded by a nuclear halo of unknown composition. How the halo is formed and regulated is unknown. We used forward genetics to identify molecular lesions behind three classical fer (fertilization defective) mutations that disrupt the ultrastru...

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Literature Corpus work: ef29d9cd-ca1b-53bc-a136-d893a4ebc3ba
DOI: 10.1101/301291

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