Article

Somatic nuclear blebbing may indicate proliferating germ cells but does not indicate organismal aging in Caenorhabditis elegans

2022-09-17

Abstract excerpt

Abnormal nuclear morphology is suggested to be a hallmark of aging. One type of such abnormalities is nuclear blebbing, but little is known about whether and how nuclear blebbing participates in animal aging. What regulates nuclear blebbing is also unknown. In this study, we show that the frequency of nuclear blebbing in the hypodermis increases during aging in wild-type C. elegans . These nuclear blebs are envel...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0bd6579f-2018-5859-b08c-4d504382d8d7
DOI: 10.1101/2022.09.17.508355

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Somatic nuclear blebbing may indicate proliferating germ cells but does not indicate organismal aging in Caenorhabditis elegansDOI 10.1101/2022.09.17.508355Read

Heat stress-induced condensation of G3BP1 in perinuclear P-bodies in C. elegans’ germlineSemantic proximity Read

cep-1/p53-dependent dysplastic pathology of the aging C. elegans gonadSemantic proximity Read

Binucleate germ cells in Caenorhabditis elegans are removed by physiological apoptosisSemantic proximity Read

Loss of intestinal nuclei and intestinal integrity in aging C. elegans.Semantic proximity Read

Nuclear lipid droplets and nuclear damage in Caenorhabditis elegans.Semantic proximity Read

Endomitosis controls tissue-specific gene expression during developmentSemantic proximity Read

The E3 ubiquitin ligase MIB-1 is necessary to form the nuclear halo in C. elegans spermSemantic proximity Read

EGO-1, a Putative RNA-Directed RNA Polymerase, Promotes Germline Proliferation in Parallel With GLP-1/Notch Signaling and Regulates the Spatial Organization of Nuclear Pore Complexes and Germline P Granules in Caenorhabditis elegansSemantic proximity Read

Gliotoxin reverses age-dependent nuclear morphology phenotypes, ameliorates motility, but fails to affect lifespan of adult Caenorhabditis elegans.Semantic proximity Read

A Practical Use of CellProfiler for Image Analysis of Germ Cells in Caenorhabditis elegansSemantic proximity Read

Caenorhabditis elegans as a model system for studying the nuclear lamina and laminopathic diseases.Semantic proximity Read

Somatic Programmed DNA Elimination is widespread in free-living Rhabditidae nematodesSemantic proximity Read

Somatic nuclear blebbing may indicate proliferating germ cells but does not indicate organismal aging in <i>Caenorhabditis elegans</i>

Abstract excerpt

Topics

Identifiers and source

Related research