Article
Nucleation-dependent aggregation kinetics of Yeast <i>Sup</i> 35 fragment GNNQQNY
2020-07-28
Abstract excerpt
An N-terminal hepta-peptide sequence of yeast prion protein Sup35 with the sequence GNNQQNY serves as an ideal model for structural understanding of amyloid assembly and kinetics. In this study, we used a reproducible solubilisation protocol that allows the generation of homogenous monomeric solution of GNNQQNY to understand the molecular details of its self-assembly mechanism. The aggregation kinetics data show t...
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Identifiers and source
- Literature Corpus work
- eeb4bcd0-6ac9-5890-a5a6-6b9da78962fb
- DOI
- 10.1101/2020.07.27.221150
