Article

Retarded DSB repair kinetics suggestive of augmented radiation sensitivity and genetic instability in Wiskott-Aldrich syndrome patients

2025-01-31

Abstract excerpt

<title>Abstract</title> <p>Wiskott-Aldrich Syndrome (WAS) is a rare X-linked recessive disorder characterized by microthrombocytopenia, eczema, combined immunodeficiency, and an increased risk of malignancies. Previous research has highlighted genomic instability in WAS patients; however, the specific dynamics of double-strand break (DSB) repair in these individuals are not fully understood. Phosphorylation of γH...

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Literature Corpus work: ee9038d7-8fba-5885-bb9c-0446ab9e76bd
DOI: 10.21203/rs.3.rs-5719467/v1

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