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Article

Evaluation of Severe Combined Immunodeficiency and Combined Immunodeficiency Pediatric Patients on the Basis of Cellular Radiosensitivity.

The Journal of molecular diagnostics : JMD - 1 Sept 2015

Lobachevsky Pavel, Woodbine Lisa, Hsiao Kuang-Chih, Choo Sharon, Fraser Chris, Gray Paul, Smith Jai, Best Nickala, Munforte Laura, Korneeva Elena, Martin Roger F, Jeggo Penny A, Martin Olga A

Abstract excerpt

Pediatric patients with severe or nonsevere combined immunodeficiency have increased susceptibility to severe, life-threatening infections and, without hematopoietic stem cell transplantation, may fail to thrive. A subset of these patients have the radiosensitive (RS) phenotype, which may necessitate conditioning before hematopoietic stem cell transplantation, and this conditioning includes radiomimetic drugs,...

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Identifiers

PMID: 26151233
DOI: 10.1016/j.jmoldx.2015.05.004
PMCID: PMC4597279

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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