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A dynamic miRNA-mRNA network serves as a crosstalk between abnormal cell cycle and immunosuppressive microenvironment in the colorectal adenoma-carcinoma sequence

2023-10-18

Abstract excerpt

<h4>Background: </h4> Colorectal tumorigenesis is well accepted with the colorectal adenoma-carcinoma sequence (ACS). MicroRNAs (miRNAs) have been considered as effective biomarkers for colorectal cancer (CRC) or adenoma detection. However, it is unclear how miRNAs initiate CRC. Methods In our study, we collected multiple public datasets with miRNA (GSE41655 and GSE115513) or mRNA (GSE41657 and GSE37364) consisti...

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Literature Corpus work
ee570eee-f6c1-5528-a42b-1c5e304c4556
DOI
10.21203/rs.3.rs-3403121/v1
Open publication

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A dynamic miRNA-mRNA network serves as a crosstalk between abnormal cell cycle and immunosuppressive microenvironment in the colorectal adenoma-carcinoma sequenceDOI 10.21203/rs.3.rs-3403121/v1
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