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Water Extract of Senecio scandens Buch.-Ham. Ameliorates Allergic Contact Dermatitis by Targeting MrgprB2 and Restoring Sustained Potassium Currents in Dorsal Root Ganglion Neurons

2026-08-14

Abstract excerpt

<title>Abstract</title> <p> Background Allergic contact dermatitis (ACD) is a common type IV hypersensitivity skin disorder characterized by recurrent inflammatory lesions and persistent pruritus. Although glucocorticoids are first-line treatments, their long-term use is limited by adverse effects. Mas-related G protein-coupled receptor B2 (MrgprB2) is a key regulator of allergic pruritus. Water extract of <it...

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Literature Corpus work: ee259131-6ba4-5b26-9d44-1284f8a1dfe2
DOI: 10.21203/rs.3.rs-10680607/v1

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Water Extract of Senecio scandens Buch.-Ham. Ameliorates Allergic Contact Dermatitis by Targeting MrgprB2 and Restoring Sustained Potassium Currents in Dorsal Root Ganglion NeuronsDOI 10.21203/rs.3.rs-10680607/v1Read

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