Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of potential causal metabolites associated with atopic dermatitis.

Human molecular genetics - 18 May 2023

Jia Yiming, Wang Rong, Sun Lulu, Guo Daoxia, Shi Mengyao, Zhang Kaixin, Yang Pinni, Wang Yu, Liu Fanghua, Chen Guo-Chong, Zhang Yonghong, Zhu Zhengbao

Abstract excerpt

Atopic dermatitis is a chronically recurrent dermatologic disease affected by complex pathophysiology with limited therapeutic options. To identify promising biomarkers for atopic dermatitis, we conducted a Mendelian randomization (MR) study to systematically screen blood metabolome for potential causal mediators of atopic dermatitis and further predict target-mediated side effects. We selected 128 unique blood...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers
Share to Dermatitis, Atopic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Docosahexaenoic Acids

Share to Genome-Wide Association Study

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Source

Identifiers

PMID: 36637422
DOI: 10.1093/hmg/ddad005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of potential causal metabolites associated with atopic dermatitis.PMID 36637422Read ↗

Causal relationships of metabolites with allergic diseases: a trans-ethnic Mendelian randomization studySemantic proximity Read ↗

The Causal Relationship Between Circulating Metabolites and the Risk of Atopic Dermatitis: A Two-Sample Mendelian Randomization StudySemantic proximity Read ↗

Genetically determined metabolites in allergic conjunctivitis: A Mendelian randomization studySemantic proximity Read ↗

Unraveling the Causal Relationship Between Blood Metabolites and Acne: A Metabolomic Mendelian Randomization Study.Semantic proximity Read ↗

Phenome-wide Mendelian randomization analysis reveals new risk factors for 4 inflammatory skin diseases.Semantic proximity Read ↗

The levels of amino acid metabolites in serum induce the pathogenesis of atopic dermatitis by mediating the inflammatory protein S100A12.Semantic proximity Read ↗

The causal relationship between serum metabolites and acne vulgaris: a Mendelian randomization study.Semantic proximity Read ↗

Identifying serum metabolite biomarkers for autoimmune diseases: a two-sample mendelian randomization and meta-analysisSemantic proximity Read ↗

Causal effects of circulating lipids and lipid-lowering drugs on the risk of atopic dermatitis: a mendelian randomization study.Semantic proximity Read ↗

Causal association of gut microbes and blood metabolites with acne identified through systematic mendelian randomization.Semantic proximity Read ↗

The causal relationship and potential mediators between plasma lipids and atopic dermatitis: a bidirectional two-sample, two-step mendelian randomization.Semantic proximity Read ↗

Causal relationship and mediation effects of immune cells and plasma metabolites in atopic dermatitis: A Mendelian randomization study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.