Article

Insights into the structure and function of the human organic anion transporter 1 in lipid bilayer membranes

2022-01-12

Abstract excerpt

The human SLC22A6/OAT1 plays an important role in the elimination of a broad range of endogenous substances and xenobiotics thus attracting attention from the pharmacological community. Furthermore, OAT1 is also involved in key physiological events such as the remote inter-organ communication. Despite its significance, the knowledge about h OAT1 structure and the transport mechanism at the atomic level remains fr...

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Literature Corpus work: ee11a6dd-b2ea-5a67-8186-80320634a809
DOI: 10.1101/2022.01.10.475390

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