Article

Deletion of TRIB3 Disrupts the Tumor Progression Induced by Integrin αvβ3 in Lung Cancer

2021-07-09

Abstract excerpt

<h4>Background: </h4> Integrin αvβ3 have been proposed as crucial determinant for tumor sustained progression and a molecular marker for the estimation of tumor angiogenesis.Our study presented that integrin αvβ3 could efficiently promote the lung cancer proliferation and stem-like phenotypes. And this process is in a tribbles homolog 3 (TRIB3) dependent manner. <h4>Result: </h4> Mechanistically, integrin αvβ3 cou...

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Literature Corpus work: edf7a8a4-cfbc-5351-a988-c91cba027fe2
DOI: 10.21203/rs.3.rs-601624/v1

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