Article

Down-regulation of<i>MALAT1</i>is a hallmark of tissue and peripheral proliferative T cells in COVID-19

2023-01-07

Abstract excerpt

T cells play key protective but also pathogenic roles in COVID-19. We studied expression of long non-coding RNAs (lncRNAs) in COVID-19 T cell transcriptomes by integrating previously published single-cell RNA sequencing datasets. The long intergenic non-coding RNA MALAT1 was the most highly transcribed lncRNA in T cells, with Th1 cells demonstrating the lowest and CD8+ resident memory cells the highest MALAT1 expr...

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Literature Corpus work: edf18815-5596-56ab-8e58-762f8c403ae3
DOI: 10.1101/2023.01.06.23284229

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