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Transcriptomic Profiling Reveals Key Molecular Events and Pathways Driving Acquired Chemotherapy Resistance in Relapsed Acute Myeloid Leukemia

2025-12-26

Abstract excerpt

<h4>Background: </h4> Acute myeloid leukemia (AML) is a highly heterogeneous hematologic malignancy. Although induction therapy induces remission in many patients, relapse and acquired chemoresistance remain the major causes of treatment failure. Defining the molecular mechanisms underlying relapse is essential for improving therapeutic strategies. <h4>Methods:</h4> Bone marrow samples from nine AML patients were...

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Literature Corpus work
eddfc200-8e7d-5d4d-b245-0a4c75436c4a
DOI
10.64898/2025.12.24.696467
Open publication

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Transcriptomic Profiling Reveals Key Molecular Events and Pathways Driving Acquired Chemotherapy Resistance in Relapsed Acute Myeloid LeukemiaDOI 10.64898/2025.12.24.696467
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