Article

A convex optimization framework for gene-level tissue network estimation with missing data and its application in understanding disease architecture

2020-03-18

Abstract excerpt

Genes with correlated expression across individuals in multiple tissues are potentially informative for systemic genetic activity spanning these tissues. In this context, the tissue-level gene expression data across multiple subjects from the Genotype Tissue Expression (GTEx) Project is a valuable analytical resource. Unfortunately, the GTEx data is fraught with missing entries owing to subjects often contributing...

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Literature Corpus work: edcadc3f-cd80-55a6-8a99-eb1b49f9d122
DOI: 10.1101/2020.03.16.994020

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