Article

The effect of APOE genotype and streamline density volume, on hippocampal CA1 down-regulation: a real-time fMRI virtual reality neurofeedback study

2019-05-21

Abstract excerpt

Hippocampal hyperactivity is a precursor of Alzheimer’s disease and more prominent in APOE-ε4 carriers. It is therefore important to investigate the processes of hippocampal self-regulation, to monitor therapeutic efficacy of preclinical interventions. We have developed a closed-loop, virtual reality neurofeedback paradigm for real-time fMRI, that provides a standardized method for quantifying processes of hippoca...

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Literature Corpus work: ed9f763f-fd26-5374-8034-b20eab9b299b
DOI: 10.1101/643577

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