Article

Developmental PBDE exposure impairs histamine release from mast cells by altering granule maturation and calcium signaling in adult male and female mice

2025-07-03

Abstract excerpt

Polybrominated diphenyl ethers (PBDEs) are synthetic flame retardants once widely used in furniture, electronics, and other consumer products. Although phased out in the early 2000s, their persistence and recycling into new materials have led to continued environmental contamination and widespread human exposure —particularly through diet and indoor dust. Developing individuals face the highest exposure due to pla...

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Literature Corpus work: ed9c3412-cb38-50b0-a8fa-349168fff709
DOI: 10.1101/2025.06.28.661534

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