Article

Prenatal benzene exposure alters offspring hypothalamic development predisposing to metabolic disease in later life

2023-01-05

Abstract excerpt

The hypothalamus is essential in the regulation of metabolism, notably during critical windows of development. An abnormal hormonal and inflammatory milieu during development can trigger persistent changes in the function of hypothalamic circuits, leading to long-lasting effects on the body’s energy homeostasis and metabolism. We recently demonstrated that gestational exposure to benzene at smoking levels induces...

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Literature Corpus work: 3f894f68-1c7d-54ee-b63e-397465efe3d4
DOI: 10.1101/2023.01.05.522910

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