Alterations of Gut Microbiome and Metabolite Profiling in Mice Infected by Schistosoma japonicum

Abstract excerpt

Schistosoma japonicum (S. japonicum) is one of the etiological agents of schistosomiasis, a widespread zoonotic parasitic disease. However, the mechanism of the balanced co-existence between the host immune system and S. japonicum as well as their complex interaction remains unclear. In this study, the 16S rRNA gene sequencing combined with metagenomic sequencing approach, as well as UPLC-MS metabolic profiling...

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