Article

The Human Mesenchymal Stem Cell Secretome Directs Macrophage Differentiation in an Oxygen-Dependent Manner

2023-06-26

Abstract excerpt

<title>Abstract</title> <p>Background Chronic disease states can share inflammation as an underlying pathology. Macrophages are associated with chronic inflammation; in general, M1 phenotype macrophage activity inhibits cell proliferation and causes tissue damage whilst M2 macrophages promote proliferation and tissue repair. Human mesenchymal stem/stromal cells (hMSCs) are of particular interest for immunoregula...

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Literature Corpus work: ed6abe87-aef6-527c-ade1-227209a11a53
DOI: 10.21203/rs.3.rs-3006436/v1

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