Article
Proteomic Signature Reveals Modulation of Human Macrophage Polarization and Functions Under Differing Environmental Oxygen Conditions.
Molecular & cellular proteomics : MCP - 1 Dec 2017
Court Magali, Petre Graciane, Atifi Michèle El, Millet Arnaud
Abstract excerpt
Macrophages are innate immune cells which can react to a large number of environmental stimuli thanks to a high degree of plasticity. These cells are involved in a variety of tissue functions in homeostasis, and they play essential roles in pathological contexts. Macrophages' activation state, which determines their functional orientation, is strongly influenced by the cellular environment. A large body of...
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