Article
Human Mesenchymal Stromal Cell Sheets Induce Macrophages Predominantly to an Anti-Inflammatory Phenotype.
Stem cells and development - 1 Jul 2018
Sukho Panithi, Hesselink Jan Willem, Kops Nicole, Kirpensteijn Jolle, Verseijden Femke, Bastiaansen-Jenniskens Yvonne M
Abstract excerpt
Tissue healing is a highly complex process involving a cascade of biochemical and cellular events. Excessive inflammation can impair the healing response. Previous in vitro studies have shown that mesenchymal stromal cells can modulate macrophage-induced inflammation and, therefore, are promising candidates for cell-based therapies aimed at promoting tissue repair. Recently, cell sheets were introduced as a new...
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