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Tissue and Cell-Free DNA-Based Epigenomic Approaches for Cancer Detection

16 Dec 2019

Abstract excerpt

BACKGROUND: Over 9 million people die of cancer each year worldwide, reflecting the unmet need for effective biomarkers for both cancer diagnosis and prognosis. Cancer diagnosis is complex because the majority of malignant tumors present with long periods of latency and lack of clinical presentation at early stages. During carcinogenesis, premalignant cells experience changes in their epigenetic landscapes, such...

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PMID: 31843869
DOI: 10.1373/clinchem.2019.303594

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