Article
[Epigenetics of cancer].
Gastroenterologia y hepatologia - 1 Jan 2008
Gonzalo Victoria, Castellví-Bel Sergi, Balaguer Francesc, Pellisé Maria, Ocaña Teresa, Castells Antoni
Abstract excerpt
The pathogenesis of cancer includes both genetic and epigenetic mechanisms. The term <<epigenetic>> refers to any alteration of gene expression, potentially hereditary, which is not accompanied by a modification in the DNA sequence. The effects of epigenetic changes include alteration of DNA transcription, aberrant activation of specific genes, predisposition of genetic instability through alteration of the...
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