Article

Archetypal Analysis for Population Genetics

2021-11-29

Abstract excerpt

The estimation of genetic clusters using genomic data has application from genome-wide association studies (GWAS) to demographic history to polygenic risk scores (PRS) and is expected to play an important role in the analyses of increasingly diverse, large-scale cohorts. However, existing methods are computationally-intensive, prohibitively so in the case of nationwide biobanks. Here we explore Archetypal Analysis...

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Literature Corpus work: ed45c2a9-d470-5cca-ad73-725108d8ee08
DOI: 10.1101/2021.11.28.470296

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