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Hybrid Autoencoder with Orthogonal Latent Space for Robust Population Structure Inference

2022-06-17

Abstract excerpt

<h4>Background</h4> Analysis of population structure and genomic ancestry remains an important topic in human genetics and bioinformatics. Commonly used methods require high-quality genotype data to ensure accurate inference. However, in practice, laboratory artifacts and outliers are often present in the data. Moreover, existing methods are typically affected by the presence of related individuals in the dataset...

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Literature Corpus work
4a721b38-1774-51fe-9b3b-1a7294d020a6
DOI
10.1101/2022.06.16.496401
Open publication

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Hybrid Autoencoder with Orthogonal Latent Space for Robust Population Structure InferenceDOI 10.1101/2022.06.16.496401
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