Article

NMDA receptor modulation and severe acute respiratory syndrome treatment

2021-10-18

Abstract excerpt

N-Methyl-D-aspartate (NMDA) subtype of glutamate receptors is expressed in the human lungs and central nervous system. NMDA receptor potentiation could increase calcium ion influx and promote downstream signaling mechanisms associated with cellular contractions that are disrupted in severe acute respiratory syndrome. Pharmacological effects generated by triggering glutamate receptor function in the brain, coupled...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ed1c16ef-9b08-5489-885a-32d01f1f7a9d
DOI: 10.12688/f1000research.73897.1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

NMDA receptor modulation and severe acute respiratory syndrome treatmentDOI 10.12688/f1000research.73897.1Read

NMDA Receptor Potentiation and Severe Acute Respiratory Syndrome TreatmentSemantic proximity Read

Modulators of voltage-dependent calcium channels for the treatment of nervous system diseases.Semantic proximity Read

Inflammatory mediators mediate airway smooth muscle contraction through a G protein-coupled receptor-transmembrane protein 16A-voltage-dependent Ca2+ channel axis and contribute to bronchial hyperresponsiveness in asthma.Semantic proximity Read

Clinical Application of the Muscle-Relaxant Effects of Magnesium in Anaesthesia: Data from Randomized Trials and Meta-AnalysisSemantic proximity Read

Targeting NMDAR2A: Esketamine's Impact on BV2 Microglial Pro-inflammatory PolarizationSemantic proximity Read

Structural insights into competitive antagonism in NMDA receptors.Semantic proximity Read

Migraine pathophysiology : NR2A/SFKs signaling in cortical spreading depressionSemantic proximity Read

Neurochemical phenotypes of cardiorespiratory neurons.Semantic proximity Read

Acute lung injury induces sustained neuroinflammation and dysfunction in the brainstem nucleus of the solitary tract of ratsSemantic proximity Read

GABA administration limits viral replication and pneumonitis in a mouse model of COVID-19Semantic proximity Read

Clinical Outcomes of Implementing Two Management Protocols for Acute Respiratory Distress Patients with COVID-19: A Randomized Controlled TrialSemantic proximity Read

The DREAM protein negatively regulates the NMDA receptor through interaction with the NR1 subunit.Semantic proximity Read