Article
A molecular taxonomy of tumors independent of tissue-of-origin
2020-08-27
Abstract excerpt
Cancer is a complex disease involving disrupted cellular metabolism, basic biochemical processes, and the microenvironment. However, despite some generally agreed upon unifying principles (Hanahan and Weinberg 2000, 2011), molecular signatures remain largely indistinguishable from tissue-of-origin, presenting a major barrier for precision health and individualized medicine. To address this challenge, we reduce mut...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- ed1a1444-c746-5698-840d-f81fb560cf49
- DOI
- 10.1101/2020.08.26.268987