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Article

A multilevel pan-cancer map links gene mutations to cancer hallmarks.

Chinese journal of cancer - 14 Sept 2015

Knijnenburg Theo A, Bismeijer Tycho, Wessels Lodewyk F A, Shmulevich Ilya

Abstract excerpt

BACKGROUND: A central challenge in cancer research is to create models that bridge the gap between the molecular level on which interventions can be designed and the cellular and tissue levels on which the disease phenotypes are manifested. This study was undertaken to construct such a model from functional annotations and explore its use when integrated with large-scale cancer genomics data. METHODS: We created...

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Identifiers

PMID: 26369414
DOI: 10.1186/s40880-015-0050-6
PMCID: PMC4593384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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