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Broadly neutralizing antibody-secreting CAR-T cells elicit Fc-mediated effector functions <i>in vitro</i> and suppress HIV in humanized mice

2026-03-12

Abstract excerpt

Despite significant advances in antiretroviral therapy (ART) that have transformed human immunodeficiency virus (HIV) infection from a fatal diagnosis to a manageable chronic condition, the persistent viral reservoir necessitates lifelong treatment underscoring the critical need for curative interventions. Viral persistence within anatomically distinct reservoirs, coupled with HIV-associated immune dysregulation a...

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Literature Corpus work
ed12c3df-48af-52bd-98d0-f0d7897e4dc4
DOI
10.64898/2026.03.10.710742
Open publication

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Broadly neutralizing antibody-secreting CAR-T cells elicit Fc-mediated effector functions <i>in vitro</i> and suppress HIV in humanized miceDOI 10.64898/2026.03.10.710742
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